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n the United States, over 40% of adults suffer from obesity, making it an increasing problem. Dieting and exercise are two common traditional weight loss methods that might be challenging to keep up with over time which is why many are looking to alternative methods that work. One such is Semaglutide — a novel idea that’s now demonstrating potential in the treatment of obesity.
What is Semaglutide?
Semaglutide belongs to a group of medicines called “glucagon-like peptide-1 (GLP-1) agonists.” GLP-1, a hormone that the body produces after eating, is mimicked by these medications to act as an appetite suppressant. The hormone GLP-1 is involved in controlling blood sugar levels, and also hunger and digestion. The effects of Semaglutide include decreased appetite, elevated fullness levels, and slowed digestion.
The FDA (Food and Drug Administration) has approved Semaglutide for the treatment of type 2 diabetes. It has also been investigated more recently for its ability to aid in weight loss. According to these investigations, in a year, Semaglutide users — on average — shed 15% of their body weight. Comparatively, the average weight reduction from other weight-loss drugs is between 5% and 10%. Beyond weight loss, Semaglutide has also been demonstrated to reduce blood pressure and cholesterol levels.
What are the benefits of Semaglutide?
Semaglutide provides a ton of benefits, including:
- Achieving a significant weight loss goal.
- Reduced risk of developing obesity-related diseases, like type 2 diabetes and heart disease.
- Improved physical function, mood, and quality of life.
- Increased energy levels.
- Reduced food cravings and hunger.
- Decreased body fat and increased lean body mass.
Possible side effects of Semaglutide
- Nausea: During the first several weeks of Semaglutide medication, nausea is a frequent adverse effect. Often, it can be controlled by beginning with a lesser dose and gradually raising it as your body becomes accustomed to it. Staying hydrated and eating smaller, more frequent meals can also help reduce nausea.
- Vomiting: Some people may vomit, particularly at first. It’s crucial to stay hydrated and frequently touch base with your doctor if this happens. It could be required to change the dosage or briefly stop taking the drug.
- Diarrhea: Diarrhea is another possible side effect. A balanced diet and excellent hydration as well as good hygiene can be beneficial. Consult your doctor if the diarrhea doesn’t go away.
- Constipation: On the other side, some individuals may have constipation. This adverse effect can be managed by increasing fiber intake through foods or supplements, being active, and staying hydrated.
- Redness at injection site: Redness, itching, or irritation at the injection site are possible reactions. Applying a cold compress after injection and rotating injection sites may ease the pain.
- Hypoglycemia: Semaglutide can drop blood sugar levels, which could lead to hypoglycemia (low blood sugar). It’s important to monitor your blood sugar levels, especially if you’re also on other diabetes drugs. In case of a hypoglycemic episode, keep some candy or a source of glucose close at hand.
- Pancreatitis: Although uncommon, pancreatitis is a potentially harmful adverse effect. Watch out for signs like ongoing or severe stomach discomfort, and call your doctor immediately.
- Thyroid cancer: Semaglutide has been linked to a higher risk of thyroid cancer. For patients using the treatment, routine thyroid exams are advised.
- Gallbladder problems: Certain people could have gallbladder-related issues. Consult a doctor if you have persistent stomach pain or other symptoms.
- Kidney complications: It is important to regularly check renal function while using Semaglutide because it can occasionally affect kidney health.
- Allergic reaction: Allergic reactions occur occasionally. Consult a doctor immediately if you get symptoms including a rash, itching, swelling, severe vertigo, or breathing difficulties.
- Fatigue: Administration of this medicine can make you feel worn out or tired. This can be controlled with sufficient sleep, a healthy diet, and regular exercise.
What does your doctor need to know before prescribing?
The following are some important information to provide your doctor before receiving this medication:
- Medical history: Your doctor will inquire about your medical history, including any existing medical conditions, such as diabetes, thyroid disorders, pancreatitis, kidney problems, or cardiovascular issues.
- Medications: Inform your doctor about all the medications you are currently taking, including prescription medications, over-the-counter drugs, supplements, and herbal remedies. This helps prevent potential interactions with Semaglutide.
- Allergies: Any known allergies to medications or other substances should be communicated to your doctor.
- Pregnancy/breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, your doctor needs to be informed. The use of Semaglutide during pregnancy or breastfeeding has to be discussed and evaluated.
- Previous treatments: Share details about any previous weight loss treatments or interventions you’ve tried as well as their outcomes.
- Diabetes management: If you have diabetes, your doctor will need to know about your current diabetes management plan and medications.
- Thyroid health: Your doctor might ask about your thyroid function as Semaglutide can impact thyroid health.
- Gallbladder issues: If you’ve had gallbladder problems in the past, your doctor should be aware as Semaglutide might affect gallbladder function.
- Kidney function: Your kidney function will likely be assessed as Semaglutide can influence kidney health.
- Cardiovascular health: Your doctor might inquire about your cardiovascular history, including heart disease, stroke, or other cardiovascular conditions.
- Lifestyle and habits: Information about your diet, exercise routine, alcohol consumption, and smoking habits can provide a more comprehensive understanding of your health profile.
- Current health status: Your doctor will want to know how you’re feeling currently and if you’re experiencing any symptoms that might impact your suitability for Semaglutide treatment.
Featured image: Liudmila Chernetska/iStock
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